Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 13/20 | 0.40 |
| ▸ | TP53 | P04637 | 11/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27482758 | 0.88 | MDM2 (0.41) | MDM2TP53HTR2AHTR2CHTR2B | |
| SCHEMBL27483135 | 0.85 | HDAC8 (0.41) | SLC6A3 | |
| SCHEMBL27706017 | 0.83 | MAPT (0.39) | CHRM3 | |
| SCHEMBL27468095 | 0.79 | SLC6A4 (0.33) | SLC6A3 | |
| SCHEMBL27482760 | 0.78 | HPGD (0.33) | SLC6A3 | |
| SCHEMBL27515302 | 0.78 | HDAC8 (0.41) | SLC6A3 | |
| SCHEMBL27466722 | 0.73 | HDAC8 (0.48) | — | |
| SCHEMBL9781187 | 0.70 | HTR2A (0.55) | MDM2TP53HTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL27655953 | 0.69 | MEN1 (0.47) | HTR2AHTR2CHTR2BSLC6A3 | |
| SCHEMBL29636325 | 0.68 | CHRM2 (0.38) | SLC6A3CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1151140-C | Glucokinase activators | - | 2004-05-26 | — | — | CN | disclosed |
| CN-1349519-A | Glucokinase activators | HOFFMANN LA ROCHE (CH) | 2002-05-15 | — | — | CN | disclosed |