Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.47 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27691759 | 0.82 | MAPK1 (0.55) | NPSR1KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL28770175 | 0.79 | GAA (0.51) | GAANPSR1RXFP1KDM4EESR1 | |
| SCHEMBL26970100 | 0.79 | NPSR1 (0.58) | GAANPSR1RXFP1KDM4EESR1 | |
| SCHEMBL16315254 | 0.77 | GAA (0.69) | GAANPSR1RXFP1KDM4EESR1 | |
| SCHEMBL25210194 | 0.76 | GAA (0.58) | GAANPSR1RXFP1KDM4EESR1 | |
| SCHEMBL25266463 | 0.76 | GAA (0.58) | GAANPSR1RXFP1KDM4EESR1 | |
| SCHEMBL14986443 | 0.76 | GAA (0.67) | GAANPSR1RXFP1KDM4EESR1 | |
| SCHEMBL6362085 | 0.74 | GAA (0.75) | GAANPSR1RXFP1KDM4EESR1 | |
| SCHEMBL27263380 | 0.74 | GAA (0.75) | GAANPSR1RXFP1KDM4EESR1 | |
| SCHEMBL13753379 | 0.74 | ALDH1A1 (0.63) | GAANPSR1RXFP1KDM4EESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101213195-B | Substituted glycinamides with antithrombotic and factor XA-inhibiting action | BOEHRINGER INGELHEIM INT | 2012-05-09 | — | — | CN | disclosed |
| CN-101213195-A | Substituted glycinamides having an antithrombotic and factor xa-inhibiting effect | BOEHRINGER INGELHEIM INT (DE) | 2008-07-02 | — | — | CN | disclosed |