Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18612961 | 0.85 | TSHR (0.38) | TSHRTDP1 | |
| SCHEMBL11461590 | 0.82 | TSHR (0.35) | TSHRTDP1 | |
| SCHEMBL5932950 | 0.79 | TSHR (0.33) | TSHRTDP1ALDH1A1 | |
| SCHEMBL5933574 | 0.75 | MMP8 (0.31) | TSHRTDP1 | |
| SCHEMBL277164 | 0.75 | TSHR (0.32) | TSHRTDP1 | |
| SCHEMBL19352958 | 0.75 | TSHR (0.30) | TSHRTDP1 | |
| SCHEMBL1678167 | 0.72 | — | — | |
| SCHEMBL19020934 | 0.72 | — | — | |
| SCHEMBL9599637 | 0.71 | — | — | |
| SCHEMBL1678713 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 188 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240173345-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING SUBSTITUTED NUCLEOTIDE AND NUCLEOSIDE FOR TREATING VIRAL INFECTIONS | EMORY UNIVERSITY | 2024-05-30 | — | — | US | disclosed |
| US-11935311-B2 | Methods and systems for computational decoding of biological, chemical, and physical entities | NAUTILUS SUBSIDIARY, INC. (US) | 2024-03-19 | — | — | US | disclosed |
| EP-4333859-A1 | NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS, COMBINATIONS AND USES RELATED THERETO | Emory University (US) | 2024-03-13 | — | — | EP | disclosed |
| US-11857560-B2 | Pharmaceutical compositions comprising substituted nucleotides and nucleosides for treating viral infections | EMORY UNIVERSITY (US) | 2024-01-02 | — | — | US | disclosed |
| US-20230348326-A1 | CONSTRUCTION MATERIALS, COMPOSITIONS AND METHODS OF MAKING SAME | S&E INNOVATIVE TECHNOLOGIES LLC. (US) | 2023-11-02 | — | — | US | disclosed |
| US-20230340014-A1 | METHODS OF GENERATING NANOARRAYS AND MICROARRAYS | NAUTILUS SUBSIDIARY, INC. | 2023-10-26 | — | — | US | disclosed |
| EP-4231174-A2 | METHODS AND SYSTEMS FOR COMPUTATIONAL DECODING OF BIOLOGICAL, CHEMICAL, AND PHYSICAL ENTITIES | Nautilus Subsidiary, Inc. (US) | 2023-08-23 | — | — | EP | disclosed |
| US-20230257416-A1 | METHODS OF GENERATING NANOARRAYS AND MICROARRAYS | NAUTILUS SUBSIDIARY, INC. | 2023-08-17 | — | — | US | disclosed |
| US-20230221243-A1 | METHODS AND SYSTEMS FOR INTEGRATED ON-CHIP SINGLE-MOLECULE DETECTION | NAUTILUS SUBSIDIARY, INC. | 2023-07-13 | — | — | US | disclosed |
| US-20230213438-A1 | METHODS AND SYSTEMS FOR INTEGRATED ON-CHIP SINGLE-MOLECULE DETECTION | NAUTILUS SUBSIDIARY, INC. | 2023-07-06 | — | — | US | disclosed |
| EP-0945445-A1 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |
| EP-0934325-A1 | TETRAPHOSPHONATE BICYCLIC TRISANHYDRIDES | Pharmasset, Ltd. (US) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998046673-A1 | A POLYMERIC COMPOSITE MATERIAL WITH IMPROVED FLAME RESISTANCE | DUSLO, A.S. S^¿ALA (SK) | 1998-10-22 | — | — | WO | disclosed |
| WO-1998015563-A1 | TETRAPHOSPHONATE BICYCLIC TRISANHYDRIDES | PHARMASSET, LTD. (US) | 1998-04-16 | — | — | WO | disclosed |
| EP-0426196-B1 | Surface modified fillers | LONZA AG (CH) | 1994-02-23 | — | — | EP | disclosed |
| WO-1993023031-A9 | MULTIVALENT MIMETICS AND PEPTIDE MIMETICS FOR BLOCKING CARBOHYDRATE-DEPENDENT CELLULAR INTERACTION AND FOR ELICITING ANTICARBOHYDRATE T-CELL RESPONSE | — | 1994-01-20 | — | — | WO | disclosed |
| WO-1993023031-A1 | MULTIVALENT MIMETICS AND PEPTIDE MIMETICS FOR BLOCKING CARBOHYDRATE-DEPENDENT CELLULAR INTERACTION AND FOR ELICITING ANTICARBOHYDRATE T-CELL RESPONSE | THE BIOMEMBRANE INSTITUTE (US) | 1993-11-25 | — | — | WO | disclosed |
| US-5149880-A | Conversion of methylenic carbons to carbonyls | THE TEXAS A & M UNIVERSITY SYSTEM (US) | 1992-09-22 | — | — | US | disclosed |
| WO-1991010634-A1 | NITROGEN-CONTAINING AROMATIC HETEROCYCLIC LIGAND-METAL COMPLEXES AND THEIR USE FOR THE ACTIVATION OF HYDROGEN PEROXIDE AND DIOXYGEN IN THE REACTION OF ORGANIC COMPOUNDS | TEXAS A&M UNIVERSITY SYSTEM (US) | 1991-07-25 | — | — | WO | disclosed |
| EP-0426196-A1 | Surface modified fillers | LONZA AG (CH) | 1991-05-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11857560-B2 | Pharmaceutical compositions comprising substituted nucleotides and nucleosides for treating viral infections | SLC28A1, PNP, SLC28A2 | TSHR 3619/4885TDP1 978/4885ALDH1A1 1819/4885 |
| US-20240173345-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING SUBSTITUTED NUCLEOTIDE AND NUCLEOSIDE FOR TREATING VIRAL INFECTIONS | PNP, NTPCR, TYMP | TSHR 3703/4885TDP1 259/4885ALDH1A1 1853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.