Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NQO1 | P15559 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | GLA | P06280 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.36 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.36 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27403294 | 0.89 | ALDH1A1 (0.45) | ALDH1A1TSHRKMT2AHSD17B10KDM4E | |
| Ammonia Solution, Strong SCHEMBL28117799 | 0.88 | ALDH1A1 (0.44) | ALDH1A1TSHRKMT2AHSD17B10KDM4E | |
| SCHEMBL27389344 | 0.88 | ALDH1A1 (0.44) | ALDH1A1TSHRKMT2AHSD17B10KDM4E | |
| SCHEMBL28783852 | 0.88 | ALDH1A1 (0.44) | ALDH1A1TSHRKMT2AHSD17B10KDM4E | |
| SCHEMBL27508487 | 0.86 | HPRT1 (0.45) | ALDH1A1TSHRHSD17B10NQO1MAPT | |
| Sulfuric Acid SCHEMBL29065821 | 0.84 | ALDH1A1 (0.41) | ALDH1A1TSHRKMT2AHSD17B10KDM4E | |
| Benzylamine SCHEMBL28122285 | 0.83 | ALDH1A1 (0.43) | ALDH1A1TSHRKMT2AHSD17B10KDM4E | |
| SCHEMBL28203080 | 0.81 | NQO1 (0.41) | ALDH1A1TSHRKMT2AHSD17B10NQO1 | |
| Bicarbonate SCHEMBL27702695 | 0.80 | HPRT1 (0.45) | ALDH1A1NQO1MAPTHPGDCYP1A2 | |
| SCHEMBL2089665 | 0.79 | HPRT1 (0.54) | ALDH1A1TSHRHSD17B10NQO1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101223140-A | Piperidine derivatives useful in the diagnostic and therapeutic treatment of diseases depending on renin activity | NOVARTIS AG (CH) | 2008-07-16 | — | — | CN | disclosed |