Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL988863 | 0.81 | PTGDR2 (0.51) | PTGDR2ARPPARDPPARGPPARA | |
| SCHEMBL2770732 | 0.80 | AKR1C3 (0.49) | PTGDR2ARPPARDPPARGPPARA | |
| SCHEMBL988515 | 0.79 | PTGDR2 (0.47) | PTGDR2KDM4EAR | |
| SCHEMBL23991026 | 0.76 | KDM4E (0.43) | PTGDR2KDM4ETDP1CYP1A2CYP2C19 | |
| SCHEMBL12542140 | 0.73 | PTGDR2 (0.52) | PTGDR2MEN1KMT2AMRGPRX4 | |
| SCHEMBL13770251 | 0.72 | PTGDR2 (0.69) | PTGDR2PPARDMRGPRX4 | |
| SCHEMBL3920885 | 0.70 | TAAR1 (0.61) | KDM4ECYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL3009106 | 0.70 | CHRM2 (0.63) | PPARGPPARACYP1A2CYP2C19MEN1 | |
| SCHEMBL29580665 | 0.70 | CHRM2 (0.63) | PPARGPPARACYP1A2CYP2C19MEN1 | |
| SCHEMBL585016 | 0.70 | KDM4E (0.68) | KDM4EPPARDPPARGPPARAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010102154-A2 | BIARYL OXYACETIC ACID COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2010-09-10 | — | — | WO | disclosed |