Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MGAT3 | Q09327 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL987716 | 0.92 | PTGDR2 (0.57) | PTGDR2PDE4DCA12CA1CA2 | |
| SCHEMBL2769871 | 0.83 | PTGDR2 (0.58) | PTGDR2CA12CA1CA2CA4 | |
| SCHEMBL12948817 | 0.82 | PTGDR2 (0.45) | PTGDR2ARGPBAR1ALDH1A1MAPT | |
| SCHEMBL2770735 | 0.79 | PTGDR2 (0.48) | PTGDR2ARKDM4E | |
| SCHEMBL2772208 | 0.77 | PTGDR2 (0.62) | PTGDR2CA12CA1CA2CA4 | |
| SCHEMBL2773541 | 0.77 | PTGDR2 (0.58) | PTGDR2CA12CA1CA2CA4 | |
| SCHEMBL988451 | 0.77 | KEAP1 (0.46) | PTGDR2PTGER1MMP1MMP9MMP13 | |
| SCHEMBL2773959 | 0.77 | PTGDR2 (0.66) | PTGDR2CA12CA1CA2CA4 | |
| SCHEMBL2771309 | 0.77 | PTGDR2 (0.57) | PTGDR2CA12CA1CA2CA4 | |
| SCHEMBL2770545 | 0.76 | PTGDR2 (0.58) | PTGDR2CA12CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011002814-A2 | BIARYL OXYACETIC ACID COMPOUNDS | LIGAND PHARMACEUTICALS INC. (US) | 2011-01-06 | — | — | WO | disclosed |
| WO-2010102154-A2 | BIARYL OXYACETIC ACID COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2010-09-10 | — | — | WO | disclosed |