Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 13/20 | 0.59 |
| ▸ | CNR1 | P21554 | 12/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5378725 | 0.99 | CNR2 (0.58) | CNR2CNR1KCNH2OPRL1 | |
| SCHEMBL2769877 | 0.90 | CNR2 (0.60) | CNR2CNR1KCNH2OPRL1 | |
| SCHEMBL2769826 | 0.89 | CNR1 (0.59) | CNR2CNR1KCNH2 | |
| SCHEMBL2768949 | 0.86 | OPRL1 (0.60) | CNR2CNR1KCNH2OPRL1 | |
| Hydrochloric Acid SCHEMBL5384239 | 0.85 | OPRL1 (0.59) | CNR2CNR1KCNH2OPRL1 | |
| SCHEMBL1380705 | 0.82 | CNR1 (0.55) | CNR2CNR1KCNH2OPRL1 | |
| SCHEMBL5332399 | 0.81 | CNR1 (0.69) | CNR2CNR1KCNH2 | |
| SCHEMBL4563570 | 0.81 | CNR2 (0.51) | CNR2CNR1KCNH2OPRL1 | |
| SCHEMBL908820 | 0.81 | CNR2 (0.57) | CNR2CNR1KCNH2OPRL1 | |
| SCHEMBL3999243 | 0.80 | CNR1 (0.70) | CNR2CNR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720837-B1 | DERIVATIVES OF N-' (1,5-DIPHENYL-1H-PYRAZOL-3-YL) SULPHONAMIDE WITH CB1 RECEPTOR AFFINITY | SANOFI AVENTIS (FR) | 2010-04-28 | — | — | EP | disclosed |
| EP-1720837-A1 | DERIVATIVES OF N-' (1,5-DIPHENYL-1H-PYRAZOL-3-YL) SULPHONAMIDE WITH CB1 RECEPTOR AFFINITY | Sanofi-Aventis (FR) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005073197-A1 | DERIVATIVES OF N-` (1,5-DIPHENYL-1H-PYRAZOL-3-YL) SULPHONAMIDE WITH CB1 RECEPTOR AFFINITY | SANOFI-AVENTIS (FR) | 2005-08-11 | — | — | WO | disclosed |