Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.41 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22857489 | 0.78 | NR1I2 (0.50) | MMP2MMP9MMP12KDM4ENR1I2 | |
| SCHEMBL11854392 | 0.77 | SLC6A2 (0.43) | GABBR2GABBR1LMNACYP2C9CYP3A4 | |
| SCHEMBL23169070 | 0.76 | SLC6A2 (0.46) | MMP2MMP9MMP12NR1I2 | |
| SCHEMBL19478566 | 0.76 | NR1I2 (0.49) | MMP2MMP9MMP12KDM4ENR1I2 | |
| SCHEMBL27624383 | 0.75 | GABBR2 (0.42) | ALDH1A1HPGDGABBR2GABBR1LMNA | |
| SCHEMBL24138378 | 0.75 | GABBR2 (0.59) | MTNR1AMTNR1BGABBR2GABBR1LMNA | |
| SCHEMBL11853034 | 0.75 | NR1I2 (0.47) | EPHX2GABBR2GABBR1DRD3MMP2 | |
| SCHEMBL11861186 | 0.75 | NR1I2 (0.45) | LMNAMMP2MMP9MMP12NR1I2 | |
| SCHEMBL19987475 | 0.75 | NR1I2 (0.59) | MMP2MMP9MMP12KDM4ENR1I2 | |
| SCHEMBL11859305 | 0.74 | NR1I2 (0.49) | EPHX2GABBR2GABBR1DRD3MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100400512-C | Benzoic acid derivatives as modulators of PPAR alpha and gamma | ASTRAZENECA AB (SE) | 2008-07-09 | — | — | CN | disclosed |