Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL570426 | 0.89 | USP30 (0.39) | HRH3FFAR1 | |
| SCHEMBL28823942 | 0.79 | HRH3 (0.42) | HRH3KDM4E | |
| SCHEMBL23064587 | 0.79 | FFAR1 (0.46) | FFAR1 | |
| SCHEMBL27969751 | 0.77 | FFAR1 (0.41) | FFAR1 | |
| SCHEMBL28468815 | 0.77 | FFAR1 (0.41) | FFAR1 | |
| Benzene SCHEMBL28327725 | 0.77 | FFAR1 (0.41) | FFAR1 | |
| SCHEMBL27992544 | 0.76 | FFAR1 (0.40) | FFAR1 | |
| SCHEMBL27499074 | 0.75 | NOTUM (0.42) | HRH3KCNH2 | |
| Toluene SCHEMBL27791508 | 0.74 | FFAR1 (0.41) | FFAR1 | |
| SCHEMBL28742865 | 0.73 | MAPK1 (0.37) | HRH3KCNH2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101218213-A | Process for preparing phenolic 4-biphenylylazetidin-2-ones | MICROBIA INC (US) | 2008-07-09 | — | — | CN | disclosed |
| CN-101213170-A | Process for production of 4-biphenylylazetidin-2-ones | MICROBIA INC (US) | 2008-07-02 | — | — | CN | disclosed |