Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL570426 | 0.81 | USP30 (0.39) | HRH3NOTUMMAPK1MAPTLMNA | |
| SCHEMBL8000795 | 0.75 | FFAR1 (0.51) | HRH3KDM4EMAPK1ALDH1A1MAPT | |
| SCHEMBL13284750 | 0.71 | FFAR1 (0.51) | NOTUMLMNA | |
| SCHEMBL16359910 | 0.71 | HRH3 (0.45) | HRH3NOTUMKDM4ETP53MAPK1 | |
| SCHEMBL23064587 | 0.70 | FFAR1 (0.46) | — | |
| SCHEMBL1814706 | 0.70 | NOTUM (0.50) | NOTUMKDM4ETP53MAPK1ALDH1A1 | |
| SCHEMBL14724234 | 0.70 | HRH3 (0.45) | HRH3NOTUMMAPK1ALDH1A1MAPT | |
| SCHEMBL9891645 | 0.69 | NOTUM (0.53) | HRH3NOTUMKDM4ETP53MAPK1 | |
| Hydrochloric Acid SCHEMBL1818467 | 0.69 | NOTUM (0.49) | NOTUMKDM4ETP53MAPK1ALDH1A1 | |
| SCHEMBL20458161 | 0.69 | NOTUM (0.53) | HRH3NOTUMKDM4ETP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104981470-A | Amino-substituted imidazo[1,2-a]pyridinecarboxamides and their use | Bayer Pharma AG | 2015-10-14 | — | — | CN | disclosed |