Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 17/20 | 0.61 |
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27708262 | 0.95 | TLR7 (0.63) | TLR7TLR8 | |
| SCHEMBL29493231 | 0.83 | TLR7 (0.73) | TLR7TLR8 | |
| SCHEMBL3872728 | 0.83 | TLR7 (0.71) | TLR7TLR8 | |
| SCHEMBL6726382 | 0.83 | TLR8 (0.72) | TLR7TLR8 | |
| Hydrochloric Acid SCHEMBL6723809 | 0.82 | TLR8 (0.71) | TLR7TLR8 | |
| SCHEMBL25964541 | 0.82 | TLR7 (0.75) | TLR7TLR8 | |
| SCHEMBL18587594 | 0.82 | TLR7 (0.75) | TLR7TLR8 | |
| SCHEMBL27708298 | 0.81 | TSHR (0.54) | TLR7TLR8TSHRMAPK1 | |
| SCHEMBL5634434 | 0.81 | TLR7 (0.63) | TLR7TLR8 | |
| SCHEMBL5351392 | 0.81 | TLR7 (0.72) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101014596-A | Imidazoquinolinylsulfonamides, imidazopyridinylsulfonamides, and imidazo-1, 5-naphthyridinylsulfonamides | 3M INNOVATIVE PROPERTIES CO (US) | 2007-08-08 | — | — | CN | disclosed |