Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 17/20 | 0.63 |
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27708256 | 0.95 | TLR7 (0.61) | TLR7TLR8 | |
| SCHEMBL29493231 | 0.84 | TLR7 (0.73) | TLR7TLR8 | |
| SCHEMBL18587594 | 0.83 | TLR7 (0.75) | TLR7TLR8 | |
| SCHEMBL25964541 | 0.83 | TLR7 (0.75) | TLR7TLR8 | |
| SCHEMBL3863988 | 0.82 | TLR7 (0.81) | TLR7TLR8 | |
| SCHEMBL27764961 | 0.82 | TLR7 (0.68) | TLR7TLR8 | |
| SCHEMBL5351392 | 0.82 | TLR7 (0.72) | TLR7TLR8 | |
| SCHEMBL3872728 | 0.82 | TLR7 (0.71) | TLR7TLR8 | |
| SCHEMBL27708265 | 0.82 | TSHR (0.47) | TLR7TLR8 | |
| SCHEMBL5354849 | 0.81 | TLR7 (0.76) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101014596-A | Imidazoquinolinylsulfonamides, imidazopyridinylsulfonamides, and imidazo-1, 5-naphthyridinylsulfonamides | 3M INNOVATIVE PROPERTIES CO (US) | 2007-08-08 | — | — | CN | disclosed |