Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.52 |
| ▸ | PTGER1 | P34995 | 15/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2955012 | 0.98 | CYP1A2 (0.55) | CYP1A2PTGER1MRGPRX4CYP2C9TBXA2R | |
| SCHEMBL3212344 | 0.84 | PTGER1 (0.55) | CYP1A2PTGER1MRGPRX4CYP2C9TBXA2R | |
| SCHEMBL14397613 | 0.84 | CYP1A2 (0.52) | CYP1A2PTGER1MRGPRX4CYP2C9TBXA2R | |
| SCHEMBL13902814 | 0.83 | PTGER1 (0.50) | CYP1A2PTGER1CYP2C9TBXA2RPTGS1 | |
| SCHEMBL3214226 | 0.82 | CYP1A2 (0.50) | CYP1A2PTGER1MRGPRX4CYP2C9TBXA2R | |
| SCHEMBL2962415 | 0.81 | PTGER1 (0.58) | CYP1A2PTGER1MRGPRX4CYP2C9TBXA2R | |
| SCHEMBL2961699 | 0.81 | PTGER1 (0.55) | CYP1A2PTGER1CYP2C9TBXA2RPTGS1 | |
| SCHEMBL13902801 | 0.80 | PTGER1 (0.54) | CYP1A2PTGER1MRGPRX4CYP2C9TBXA2R | |
| SCHEMBL2956473 | 0.80 | PTGER1 (0.62) | CYP1A2PTGER1MRGPRX4CYP2C9TBXA2R | |
| SCHEMBL2956494 | 0.79 | PTGER1 (0.77) | CYP1A2PTGER1CYP2C9TBXA2RPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101128430-A | Pyridine compounds for the treatment of prostaglandin mediated diseases | GLAXO GROUP LTD (GB) | 2008-02-20 | — | — | CN | disclosed |