Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 11/20 | 0.62 |
| ▸ | PPARD | Q03181 | 7/20 | 0.59 |
| ▸ | LCK | P06239 | 1/20 | 0.59 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.59 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.50 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 6/20 | 0.46 |
| ▸ | PPARA | Q07869 | 6/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TLR2 | O60603 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | FABP4 | P15090 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL338175 | 1.00 | GPR84 (0.62) | GPR84PPARDLCKZDHHC20ZDHHC2 | |
| SCHEMBL6462164 | 1.00 | GPR84 (0.62) | GPR84PPARDLCKZDHHC20ZDHHC2 | |
| SCHEMBL366545 | 1.00 | GPR84 (0.62) | GPR84PPARDLCKZDHHC20ZDHHC2 | |
| SCHEMBL5550749 | 1.00 | GPR84 (0.62) | GPR84PPARDLCKZDHHC20ZDHHC2 | |
| SCHEMBL6465230 | 1.00 | GPR84 (0.62) | GPR84PPARDLCKZDHHC20ZDHHC2 | |
| SCHEMBL23829862 | 1.00 | GPR84 (0.62) | GPR84PPARDLCKZDHHC20ZDHHC2 | |
| SCHEMBL6460857 | 1.00 | GPR84 (0.62) | GPR84PPARDLCKZDHHC20ZDHHC2 | |
| SCHEMBL6463034 | 0.98 | GPR84 (0.59) | GPR84PPARDLCKZDHHC20ZDHHC2 | |
| SCHEMBL6464981 | 0.91 | GPR84 (0.50) | GPR84PPARDLCKZDHHC20ZDHHC2 | |
| SCHEMBL6464903 | 0.83 | KDM4C (0.43) | GPR84PPARDLCKZDHHC20ZDHHC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102282132-A | Inhibitors of diacylglycerol acyltransferase | — | 2011-12-14 | — | — | CN | disclosed |
| CN-102282138-A | Inhibitors of diacylglycerol acyltransferase | — | 2011-12-14 | — | — | CN | disclosed |
| CN-102239165-A | Inhibitors of diacylglycerol acyltransferase | VIA PHARMACEUTICALS INC | 2011-11-09 | — | — | CN | disclosed |
| CN-102203280-A | Diacylglycerol acyltransferase inhibitors | VIA PHARMACEUTICALS INC | 2011-09-28 | — | — | CN | disclosed |
| CN-101835757-A | Diacylglycerol acyltransferase inhibitors | HOFFMANN LA ROCHE | 2010-09-15 | — | — | CN | disclosed |
| CN-101316844-A | Inhibitors of diacylglycerol acyltransferase (DGAT) | HOFFMANN LA ROCHE (CH) | 2008-12-03 | — | — | CN | disclosed |
| CN-101171231-A | Diacylglycerol acyltransferase inhibitors | HOFFMANN LA ROCHE (CH) | 2008-04-30 | — | — | CN | disclosed |
| CN-101115711-A | Diacylglycerol acyltransferase inhibitors | HOFFMANN LA ROCHE (CH) | 2008-01-30 | — | — | CN | disclosed |