Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | EGFR | P00533 | 4/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 4/20 | 0.48 |
| ▸ | MMP2 | P08253 | 4/20 | 0.48 |
| ▸ | MMP9 | P14780 | 4/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27709775 | 0.85 | HTT (0.63) | HTTEGFRHDAC3HDAC4HDAC1 | |
| SCHEMBL27689874 | 0.83 | HTT (0.64) | HTTEGFRHDAC3HDAC4HDAC1 | |
| Guanidine SCHEMBL27709652 | 0.82 | HTT (0.58) | HTTEGFRHDAC3HDAC4HDAC1 | |
| SCHEMBL27709612 | 0.81 | HTT (0.60) | HTTEGFRHDAC3HDAC4HDAC1 | |
| Guanidine SCHEMBL27709641 | 0.79 | HTT (0.59) | HTTEGFRHDAC3HDAC4HDAC1 | |
| SCHEMBL5427400 | 0.79 | HTT (0.62) | HTTEGFRHDAC3HDAC4HDAC1 | |
| SCHEMBL27689932 | 0.79 | HTT (0.62) | HTTEGFRHDAC3HDAC4HDAC1 | |
| SCHEMBL5671839 | 0.79 | HTT (0.62) | HTTEGFRHDAC3HDAC4HDAC1 | |
| SCHEMBL6829701 | 0.77 | HTT (0.74) | HTTEGFRHDAC3HDAC4HDAC1 | |
| SCHEMBL6829697 | 0.77 | HTT (0.74) | HTTEGFRHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101111475-A | Antiviral compounds and methods | BIOTRON LTD (AU) | 2008-01-23 | — | — | CN | claimed |
| CN-101111475-B | Antiviral compounds and methods | BIOTRON LTD | 2012-09-05 | — | — | CN | disclosed |
| CN-101111475-A | Antiviral compounds and methods | BIOTRON LTD (AU) | 2008-01-23 | — | — | CN | disclosed |