Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27689875 | 0.83 | TDP1 (0.49) | TDP1SMN1; SMN2GAAGLAHTT | |
| SCHEMBL27709603 | 0.79 | EGFR (0.60) | TDP1SMN1; SMN2GAAGLAHTT | |
| SCHEMBL27689878 | 0.79 | MMP1 (0.58) | TDP1SMN1; SMN2HTTALDH1A1CYP1A2 | |
| SCHEMBL27689932 | 0.79 | HTT (0.62) | TDP1SMN1; SMN2HTTALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL11181395 | 0.78 | TDP1 (0.51) | TDP1SMN1; SMN2GAAGLAHTT | |
| Hydrochloric Acid SCHEMBL11181399 | 0.78 | TDP1 (0.51) | TDP1SMN1; SMN2GAAGLAHTT | |
| SCHEMBL1949536 | 0.77 | MAPT (0.55) | TDP1SMN1; SMN2GLAHTTALDH1A1 | |
| SCHEMBL27709606 | 0.77 | HTT (0.48) | TDP1SMN1; SMN2GLAHTTALDH1A1 | |
| SCHEMBL3118443 | 0.77 | CYP1A2 (0.62) | TDP1SMN1; SMN2HTTALDH1A1CYP1A2 | |
| SCHEMBL14504234 | 0.77 | CYP1A2 (0.62) | TDP1SMN1; SMN2HTTALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101111475-A | Antiviral compounds and methods | BIOTRON LTD (AU) | 2008-01-23 | — | — | CN | disclosed |