SCHEMBL27709792

SCHEMBL27709792

CC(C)NC(C)C.CCC(=O)OCCl

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.36
MGAM O43451 1/20 0.34
GAA P10253 1/20 0.34
SI P14410 1/20 0.34
MGAM2 Q2M2H8 1/20 0.34
ALDH1A1 P00352 2/20 0.33
CYP1A2 P05177 1/20 0.33
HPGD P15428 1/20 0.33
CYP2C19 P33261 1/20 0.33
BLM P54132 1/20 0.33
WRN Q14191 1/20 0.33
HIF1A Q16665 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
FAAH O00519 1/20 0.31
SOAT1 P35610 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL230663 0.84
Acetic Acid SCHEMBL27342317 0.78 NAAA (0.41) NAAAMGAMGAASIMGAM2
SCHEMBL27082350 0.76 NAAA (0.40) NAAAMGAMGAASIMGAM2
SCHEMBL27730149 0.75 CYP2C9 (0.33) MGAMGAASIMGAM2ALDH1A1
SCHEMBL28743245 0.72 TDP1 (0.44) ALDH1A1HPGDTDP1FAAH
Malonic Acid Diethyl Ester SCHEMBL1218139 0.71 GAA (0.71) MGAMGAASIMGAM2ALDH1A1
SCHEMBL27563065 0.69
Propionic Acid SCHEMBL3410616 0.69 FFAR3 (0.59) ALDH1A1CYP1A2CYP2C19TDP1
SCHEMBL6748059 0.69 MGAM (0.50) MGAMGAASIMGAM2
SCHEMBL698060 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101193891-A 2-thioethenyl substituted carbapenem derivatives MEIJI SEIKA KAISHA (JP) 2008-06-04 CN disclosed