SCHEMBL27710

SCHEMBL27710

O[CH]C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1226994 0.67
SCHEMBL15017786 0.67
SCHEMBL34508 0.59
SCHEMBL28820 0.59
SCHEMBL323342 0.59
SCHEMBL8841030 0.59
SCHEMBL28819 0.59
SCHEMBL8841031 0.59
SCHEMBL2771000 0.56
SCHEMBL1316019 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 890 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3674298-B9 SUBSTITUTED INDAZOLES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL FORMULATIONS CONTAINING THEM, AND THEIR USE FOR THE PREPARATION OF MEDICAMENTS Bayer Pharma AG (DE) 2024-06-19 EP claimed
US-12006303-B2 Substituted indazoles, methods for the production thereof, pharmaceutical preparations that contain said substituted indazoles, and use of said substituted indazoles to produce drugs BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2024-06-11 US claimed
WO-2024108010-A1 METHODS AND COMPOSITIONS FOR CONTROL OF PAIN AND INFLAMMATION BAYER ANIMAL HEALTH GMBH (DE) 2024-05-23 WO claimed
CN-117999515-A Photosensitive composition, cured product, display device, electronic component, and method for producing cured product 东丽株式会社 2024-05-07 CN claimed
WO-2024010784-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS VIVIDION THERAPEUTICS, INC. (US) 2024-01-11 WO claimed
EP-3674298-B1 SUBSTITUTED INDAZOLES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL FORMULATIONS CONTAINING THEM, AND THEIR USE FOR THE PREPARATION OF MEDICAMENTS Bayer Pharma AG (DE) 2024-01-10 EP claimed
EP-3872061-B1 1-PHENYL-2-PHENYLETHANE DERIVATIVE KAO CORP (JP) 2023-12-27 EP claimed
US-20230365524-A1 2,4,5-TRISUBSTITUTED 1,2,4-TRIAZOLONES USEFUL AS INHIBITORS OF DHODH BAYER AKTIENGESELLSCHAFT (DE) 2023-11-16 US claimed
EP-4260909-A2 SUBSTITUTED INDAZOLES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND THEIR USE IN THE PREPARATION OF DRUGS Bayer Pharma Aktiengesellschaft (DE) 2023-10-18 EP claimed
US-11713304-B2 2,4,5-trisubstituted 1,2,4-triazolones useful as inhibitors of DHODH BAYER AKTIENGESELLSCHAFT (DE) 2023-08-01 US claimed
US-6019986-A Parasiticidal pyrazoles PFIZER INC. (US) 2000-02-01 US claimed
EP-0933363-A1 Parasiticidal pyrazoles Pfizer Limited (GB) 1999-08-04 EP claimed
EP-0708101-B1 Piperidine derivatives, useful as neurokinin receptor antagonists ADIR (FR) 1998-12-09 EP claimed
EP-0524692-B1 Photochromatic and thermochromatic compounds and their application in polymeric materials GREAT LAKES CHEMICAL ITALIA (IT) 1997-12-17 EP claimed
US-5652246-A NEUROKININ RECEPTOR ANTAGONISTS; NERVOUS SYSTEM DISORDERS ADIR ET COMPAGNIE (FR) 1997-07-29 US claimed
US-4493840-A Antisecretory guanidine derivatives, and pharmaceutical compositions containing them IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-01-15 US claimed
US-4293555-A OXAPENICILLIN ANTIBIOTICS MERCK & CO., INC. (US) 1981-10-06 US claimed
EP-0002210-A1 6- and 6,6- disubstituted-2-substituted-pen-2-em-3-carboxylic acids; processes for their preparation and pharmaceutical compositions containing such compounds MERCK & CO. INC. (US) 1979-06-13 EP claimed
US-4069337-A 2-SUBSTITUTED-INDOLE-1-LOWER-ALKANECARBOXAMIDES HAVING ANTI-SECRETORY OR ANTI-ULCER ACTIVITY STERLING DRUG INC. (US) 1978-01-17 US claimed
US-4021448-A ANTISECRETORY AND ANTIULCER ACTIVITIES STERLING DRUG INC. (US) 1977-05-03 US claimed