SCHEMBL27711069

SCHEMBL27711069

COc1c(C(=O)O)cc(C(=O)O)c(OC)c1C

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.55
KDM4E B2RXH2 5/20 0.46
ALDH1A1 P00352 4/20 0.46
HPGD P15428 3/20 0.46
TDP1 Q9NUW8 3/20 0.46
MAPT P10636 1/20 0.46
LCK P06239 1/20 0.44
FYN P06241 1/20 0.44
PKM P14618 1/20 0.43
POLB P06746 2/20 0.42
GPR35 Q9HC97 3/20 0.41
TPMT P51580 3/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
MYC P01106 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27731624 0.87 HSD17B10 (0.52) HSD17B10KDM4EALDH1A1HPGDTDP1
SCHEMBL27601741 0.85 LCK (0.53) HSD17B10KDM4EALDH1A1HPGDTDP1
SCHEMBL20380165 0.82 HSD17B10 (0.61) HSD17B10KDM4EALDH1A1HPGDTDP1
SCHEMBL6736179 0.82 HSD17B10 (0.55) HSD17B10KDM4EALDH1A1HPGDTDP1
SCHEMBL6474002 0.81 HSD17B10 (0.46) HSD17B10KDM4EALDH1A1HPGDTDP1
SCHEMBL27887946 0.79 TPMT (0.47) HSD17B10KDM4EALDH1A1HPGDTDP1
SCHEMBL7352417 0.79 MAPT (0.45) HSD17B10KDM4EALDH1A1HPGDTDP1
SCHEMBL1434189 0.78 HSD17B10 (0.52) HSD17B10KDM4EALDH1A1HPGDTDP1
SCHEMBL27549037 0.78 HSD17B10 (0.52) HSD17B10KDM4EALDH1A1HPGDTDP1
SCHEMBL5001513 0.78 HSD17B10 (0.47) HSD17B10KDM4EALDH1A1HPGDTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101214238-B Application of Antrodia camphorata extract in inhibiting growth of tumor cells GOLDEN BIOTECHNOLOGY CORP 2010-05-19 CN disclosed
CN-101214238-A Application of Antrodia camphorata extract in inhibiting growth of tumor cells GOLDEN BIOTECHNOLOGY CORP (CN) 2008-07-09 CN disclosed