SCHEMBL27711501

SCHEMBL27711501

CCCC[Si](C)C.[NaH]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4724 0.96
Fluoride SCHEMBL27602924 0.93
SCHEMBL27869841 0.93
Hydrochloric Acid SCHEMBL28795174 0.93
SCHEMBL17090826 0.83 TSHR (0.53)
SCHEMBL502669 0.83 TSHR (0.53)
SCHEMBL17090832 0.83 TSHR (0.53)
SCHEMBL9658795 0.83 TSHR (0.53)
SCHEMBL502963 0.83 TSHR (0.53)
SCHEMBL235247 0.83 TSHR (0.53)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101103022-B New carboxylic acid amide used as XA inhititor BOEHRINGER INGELHEIM INT 2012-06-27 CN disclosed
CN-101103022-A New carboxylic acid amide used as XA inhititor BOEHRINGER INGELHEIM PHARMA (DE) 2008-01-09 CN disclosed