SCHEMBL235247

SCHEMBL235247

CCCCCCCCCCCCCCCCCC[Si](C)C

nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.53
THRB P10828 1/20 0.53
DNM1 Q05193 7/20 0.40
ALDH1A1 P00352 3/20 0.40
LMNA P02545 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
HSD17B10 Q99714 1/20 0.40
SLC22A1 O15245 1/20 0.40
EPHX1 P07099 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17090832 1.00 TSHR (0.53) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL502963 1.00 TSHR (0.53) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL502669 1.00 TSHR (0.53) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL17090753 1.00 TSHR (0.53) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL2679212 1.00 TSHR (0.53) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL476071 1.00 TSHR (0.53) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL475858 1.00 TSHR (0.53) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL17090826 1.00 TSHR (0.53) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL9658795 1.00 TSHR (0.53) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL2680340 1.00 TSHR (0.53) TSHRTHRBDNM1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 161 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118324823-A Heterofluorene rare earth compound, preparation method thereof and application thereof in olefin polymerization 中国科学院长春应用化学研究所 2024-07-12 CN claimed
WO-2013173090-A1 UV CURABLE SELF-BONDING SILICONE RUBBER MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2013-11-21 WO claimed
US-20120003689-A1 HYDROPHOBIC MAGNETIC PARTICLES AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2012-01-05 US claimed
EP-2350275-A1 HYDROPHOBIC MAGNETIC PARTICLES Agency For Science, Technology And Research (SG) 2011-08-03 EP claimed
US-7790830-B2 Swellable sol-gels, methods of making, and use thereof WOOTECH, LTD. (US) 2010-09-07 US claimed
WO-2010056200-A1 HYDROPHOBIC MAGNETIC PARTICLES AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2010-05-20 WO claimed
WO-2008023383-A1 NOVEL PROCESS FOR THE PREPARATION OF TELITHROMYCIN ALEMBIC LIMITED (IN) 2008-02-28 WO claimed
US-20080051352-A1 Novel process for the preparation of telithromycin ALEMBIC LIMITED (IN) 2008-02-28 US claimed
WO-2008007388-A1 NOVEL PROCESS FOR THE PREPARATION OF TELITHROMYCIN ALEMBIC LIMITED (IN) 2008-01-17 WO claimed
US-6713033-B2 CHEMICALLY BONDING OCTADECYLSILYL SILICA GROUPS TO SILICA GELTHEN DEACTIVATING THE REMAINING ACTIVE SILANOL GROUPS BY HIGH TEMPERATURE END CAPPING KANTO KAGAKU KABUSHIKI KAISHA (JP) 2004-03-30 US claimed
US-20020032122-A1 Process for producing hydrophilic ODS packing material made of silica gel for liquid chromatography KANTO KAGAKU KABUSHIKI KAISHA 2002-03-14 US claimed
US-5202029-A PROCESS FOR PURIFICATION OF HMG-COA REDUCTASE INHIBITORS CARON KABUSHIKI KAISHA (JP) 1993-04-13 US claimed
CN-118702765-B Method for purifying polypeptide 天津博蕴纯化装备材料科技有限公司 2024-12-24 CN disclosed
CN-118324823-A Heterofluorene rare earth compound, preparation method thereof and application thereof in olefin polymerization 中国科学院长春应用化学研究所 2024-07-12 CN disclosed
CN-117740755-A Edible vegetable oil authenticity judging method, system, equipment and medium 国家粮食和物资储备局科学研究院 2024-03-22 CN disclosed
EP-4234643-A2 ANTIFOULING COMPOSITION Jotun A/S (NO) 2023-08-30 EP disclosed
EP-0254516-A2 Novel Peptides NOVO NORDISK A/S (DK) 1988-01-27 EP disclosed
CN-86101489-A The method for preparing neo-insulin peptide and long-acting injection thereof 1987-01-21 CN disclosed
EP-0195691-A1 Process for the preparation of Insulin Precursors and process for the preparation of human insulin NOVO NORDISK A/S (DK) 1986-09-24 EP disclosed
EP-0194864-A2 Novel peptides NOVO NORDISK A/S (DK) 1986-09-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120003689-A1 HYDROPHOBIC MAGNETIC PARTICLES HAMP, CHMP4B, PRF1 TSHR 4832/4885THRB 4853/4885DNM1 1645/4885
US-20080051352-A1 Novel process for the preparation of telithromycin TREH, CYP3A7, CYP3A4 TSHR 346/4885THRB 639/4885DNM1 1913/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.