SCHEMBL27711986

SCHEMBL27711986

Cc1cc(Br)c([N+](=O)[O-])c(Br)c1Br

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.46
ALDH1A1 P00352 5/20 0.43
TDP1 Q9NUW8 3/20 0.43
GRIN2D O15399 5/20 0.40
GRIN3B O60391 5/20 0.40
GRIN1 Q05586 5/20 0.40
GRIN2A Q12879 5/20 0.40
GRIN2B Q13224 5/20 0.40
GRIN2C Q14957 5/20 0.40
GRIN3A Q8TCU5 5/20 0.40
TSHR P16473 6/20 0.38
CYP3A4 P08684 2/20 0.38
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18510270 0.80 ALDH1A1 (0.41) CYP1A2ALDH1A1TDP1GRIN2DGRIN3B
SCHEMBL28977893 0.75 GRIN2D (0.47) CYP1A2ALDH1A1TDP1GRIN2DGRIN3B
SCHEMBL22804722 0.75 CYP1A2 (0.55) CYP1A2ALDH1A1TDP1GRIN2DGRIN3B
SCHEMBL3981776 0.75 CYP1A2 (0.50) CYP1A2ALDH1A1TDP1GRIN2DGRIN3B
SCHEMBL29363774 0.75 GRIN2D (0.51) CYP1A2ALDH1A1TDP1GRIN2DGRIN3B
SCHEMBL31329961 0.75 CYP1A2 (0.50) CYP1A2ALDH1A1TDP1GRIN2DGRIN3B
SCHEMBL29366772 0.75 CYP1A2 (0.55) CYP1A2ALDH1A1TDP1GRIN2DGRIN3B
SCHEMBL22805139 0.75 GRIN2D (0.51) CYP1A2ALDH1A1TDP1GRIN2DGRIN3B
SCHEMBL4656665 0.73 MEN1 (0.37) CYP1A2ALDH1A1GRIN2DGRIN3BGRIN1
SCHEMBL20942948 0.72 CYP1A2 (0.62) CYP1A2ALDH1A1TDP1TSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101045690-A Synthetic process of para-nitrotribromotoluene ZHONGLAN LIANHAI DESIGN INST (CN) 2007-10-03 CN disclosed