Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 10/20 | 0.36 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.35 |
| ▸ | MAPK7 | Q13164 | 6/20 | 0.34 |
| ▸ | KHK | P50053 | 2/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4961532 | 0.88 | PRKDC (0.35) | PRKDCMAPK7 | |
| SCHEMBL27711989 | 0.86 | FGFR2 (0.38) | PRKDCFGFR2MAPK7KHKKIT | |
| SCHEMBL27732135 | 0.85 | MAPK7 (0.33) | PRKDCFGFR2MAPK7KHK | |
| SCHEMBL3572685 | 0.83 | MEN1 (0.46) | PRKDCFGFR2MAPK7KHKKIT | |
| SCHEMBL5604298 | 0.83 | PRKDC (0.42) | PRKDCKHKKIT | |
| SCHEMBL5604831 | 0.81 | PRKDC (0.50) | PRKDC | |
| SCHEMBL5604488 | 0.81 | PRKDC (0.47) | PRKDC | |
| SCHEMBL3571699 | 0.81 | HTR6 (0.38) | PRKDC | |
| SCHEMBL3566238 | 0.81 | ACVR1 (0.45) | PRKDCMAPK7KHK | |
| SCHEMBL27711997 | 0.80 | MAPK7 (0.36) | PRKDCFGFR2MAPK7KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101243065-A | Intermediates for the synthesis of alkylquinoline and alkylquinazoline kinase modulators and related synthetic methods | JANSSEN PHARMACEUTICA NV (BE) | 2008-08-13 | — | — | CN | disclosed |