Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD3 | O94806 | 1/20 | 0.52 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.52 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.52 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2128085 | 0.78 | TGFBR1 (0.77) | PRKD3TGFBR1PRKD1PRKD2 | |
| SCHEMBL2126398 | 0.78 | TGFBR1 (0.64) | PRKD3TGFBR1PRKD1PRKD2 | |
| SCHEMBL2128086 | 0.78 | TGFBR1 (0.56) | PRKD3TGFBR1PRKD1PRKD2 | |
| SCHEMBL12610114 | 0.73 | — | — | |
| SCHEMBL12610111 | 0.73 | — | — | |
| SCHEMBL2128905 | 0.73 | TGFBR1 (0.59) | PRKD3TGFBR1PRKD1PRKD2 | |
| SCHEMBL12609952 | 0.70 | — | — | |
| SCHEMBL12609957 | 0.70 | — | — | |
| SCHEMBL2126260 | 0.69 | TGFBR1 (0.51) | PRKD3TGFBR1PRKD1PRKD2 | |
| SCHEMBL29381400 | 0.69 | TGFBR1 (1.00) | PRKD3TGFBR1PRKD1PRKD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101171014-A | Pteridines useful as HCV inhibitors and methods for the preparation thereof | TIBOTEC PHARM LTD (IE) | 2008-04-30 | — | — | CN | disclosed |