Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 5/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.50 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.50 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.46 |
| ▸ | F10 | P00742 | 3/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.46 |
| ▸ | NEK2 | P51955 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28789911 | 0.86 | USP2 (0.70) | NOTUMUSP2AKR1C3MAPTKDM4E | |
| SCHEMBL2471787 | 0.84 | NOTUM (0.49) | NOTUMUSP2AKR1C3SYKMAPT | |
| SCHEMBL2471785 | 0.84 | NOTUM (0.49) | NOTUMUSP2AKR1C3SYKMAPT | |
| SCHEMBL1438476 | 0.83 | KMT2A (0.60) | NOTUMUSP2AKR1C3GPR119MAPT | |
| SCHEMBL18871943 | 0.83 | GPR119 (0.55) | USP2GPR119CHRNA7CHRNA10CHRNA9 | |
| SCHEMBL2263367 | 0.83 | GPR119 (0.55) | USP2GPR119CHRNA7CHRNA10CHRNA9 | |
| SCHEMBL3570102 | 0.83 | NOTUM (0.57) | NOTUMUSP2AKR1C3MAPTKDM4E | |
| SCHEMBL11962881 | 0.83 | GPR119 (0.55) | USP2GPR119CHRNA7CHRNA10CHRNA9 | |
| SCHEMBL14507628 | 0.83 | NOTUM (0.57) | NOTUMKDM4ECYP2C19 | |
| Hydrochloric Acid SCHEMBL3571310 | 0.81 | NOTUM (0.56) | NOTUMUSP2AKR1C3MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101107218-A | Novel dicarboxylic acid derivatives | BIOPROJET SOC CIV (FR) | 2008-01-16 | — | — | CN | claimed |
| CN-101107218-A | Novel dicarboxylic acid derivatives | BIOPROJET SOC CIV (FR) | 2008-01-16 | — | — | CN | disclosed |