Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.40 |
| ▸ | KIF11 | P52732 | 8/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27677076 | 0.91 | CDK8 (0.41) | KCNH2EPHX2CDK8 | |
| SCHEMBL28114587 | 0.87 | SLC1A3 (0.37) | PRSS1TMPRSS15 | |
| SCHEMBL27320326 | 0.80 | KIF11 (0.54) | KIF11PRSS1EPHX2 | |
| SCHEMBL27532791 | 0.80 | KMT2A (0.43) | PRSS1 | |
| SCHEMBL3710890 | 0.79 | KIF11 (0.51) | SLC7A5KIF11FFAR1CDK8NOTUM | |
| SCHEMBL27917095 | 0.78 | PPARG (0.39) | EPHX2P2RX7 | |
| SCHEMBL27438158 | 0.78 | KDM4E (0.51) | PRSS1 | |
| SCHEMBL27509338 | 0.78 | KMT2A (0.43) | — | |
| SCHEMBL27462444 | 0.77 | NR4A1 (0.39) | — | |
| SCHEMBL28114237 | 0.77 | CYP4F2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101107226-B | Phenoxyacetic acid derivatives useful for treating respiratory diseases | ASTRAZENECA AB | 2012-01-18 | — | — | CN | disclosed |
| CN-101107226-A | Phenoxyacetic acid derivatives useful for treating respiratory diseases | ASTRAZENECA AB (SE) | 2008-01-16 | — | — | CN | disclosed |