Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SFRP1 | Q8N474 | 2/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4617339 | 0.91 | SFRP1 (0.79) | SFRP1HTTALDH1A1POLBPDE4B | |
| SCHEMBL27733317 | 0.89 | HTT (0.65) | SFRP1HTTALDH1A1POLBLMNA | |
| SCHEMBL4616841 | 0.86 | SFRP1 (0.72) | SFRP1HTTALDH1A1POLBPDE4B | |
| SCHEMBL4617597 | 0.86 | SFRP1 (0.72) | SFRP1HTTALDH1A1POLBPDE4B | |
| SCHEMBL4617894 | 0.85 | SFRP1 (0.64) | SFRP1HTTALDH1A1POLBPDE4B | |
| SCHEMBL4618783 | 0.84 | SFRP1 (0.80) | SFRP1HTTALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL4618646 | 0.84 | SFRP1 (0.84) | SFRP1HTTALDH1A1POLBLMNA | |
| SCHEMBL6102774 | 0.83 | SFRP1 (0.68) | SFRP1HTTALDH1A1POLBPDE4B | |
| SCHEMBL4618123 | 0.83 | SFRP1 (0.84) | SFRP1HTTALDH1A1POLBLMNA | |
| SCHEMBL4616099 | 0.83 | SFRP1 (1.00) | SFRP1HTTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101208299-A | Diarylsulfone sulfonamides and use therof | WYETH CORP (US) | 2008-06-25 | — | — | CN | claimed |
| CN-101208299-A | Diarylsulfone sulfonamides and use therof | WYETH CORP (US) | 2008-06-25 | — | — | CN | disclosed |