Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 18/20 | 0.45 |
| ▸ | THRA | P10827 | 17/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3149020 | 0.85 | THRB (0.48) | THRBTHRAHTT | |
| SCHEMBL27666369 | 0.83 | THRB (0.61) | THRBTHRA | |
| SCHEMBL282942 | 0.83 | THRB (0.45) | THRBTHRAHTT | |
| SCHEMBL3155979 | 0.83 | THRB (0.47) | THRBTHRA | |
| SCHEMBL3153304 | 0.83 | THRB (0.49) | THRBTHRA | |
| SCHEMBL282291 | 0.82 | THRB (0.43) | THRBTHRAHTT | |
| SCHEMBL4963572 | 0.81 | THRB (0.46) | THRBTHRA | |
| SCHEMBL4963579 | 0.81 | THRB (0.46) | THRBTHRA | |
| SCHEMBL3160054 | 0.80 | THRB (0.71) | THRBTHRA | |
| SCHEMBL27645323 | 0.79 | THRB (0.40) | THRBTHRAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101189248-A | Novel phosphorus-containing thyromimetics | METABASIS THERAPEUTICS INC (US) | 2008-05-28 | — | — | CN | disclosed |
| CN-101180097-A | Novel phosphinic acid-containing thyromimetics | METABASIS THERAPEUTICS INC (US) | 2008-05-14 | — | — | CN | disclosed |