SCHEMBL27713166

SCHEMBL27713166

O=CC(=O)c1cc2cccc3c4cccc5cccc(c(c1)c23)c54

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
ALDH1A1 P00352 5/20 0.42
MAPK1 P28482 3/20 0.42
TDP1 Q9NUW8 2/20 0.42
CYP1A2 P05177 3/20 0.38
ERBB2 P04626 1/20 0.38
FYN P06241 1/20 0.38
MAOA P21397 1/20 0.38
ACHE P22303 1/20 0.38
AHR P35869 1/20 0.38
HPGD P15428 4/20 0.36
HSD17B10 Q99714 2/20 0.36
THRB P10828 1/20 0.36
MAPT P10636 3/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
KDM4E B2RXH2 1/20 0.35
EGFR P00533 1/20 0.35
TP53 P04637 1/20 0.35
CYP3A4 P08684 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10012128 0.78 MEN1 (0.68) MEN1KMT2AALDH1A1CYP1A2HPGD
Formic Acid SCHEMBL27906459 0.72 ALDH1A1 (0.52) MEN1KMT2AALDH1A1MAPK1TDP1
SCHEMBL12500720 0.72 ALDH1A1 (0.45) MEN1KMT2AALDH1A1MAPK1TDP1
SCHEMBL22205095 0.72 CYP1A2 (0.46) MEN1KMT2AALDH1A1MAPK1TDP1
SCHEMBL28128402 0.72 ALDH1A1 (0.47) MEN1KMT2AALDH1A1MAPK1TDP1
SCHEMBL28236960 0.71 CYP1B1 (0.54) MEN1KMT2AALDH1A1MAPK1TDP1
SCHEMBL4628576 0.71 CYP1A2 (0.50) MEN1KMT2AALDH1A1TDP1CYP1A2
SCHEMBL636521 0.71 CYP1A2 (0.50) MEN1KMT2AALDH1A1TDP1CYP1A2
SCHEMBL28171177 0.71 CYP1A2 (0.42) MEN1KMT2AALDH1A1MAPK1CYP1A2
Bicarbonate SCHEMBL3836308 0.70 CYP1A2 (0.55) MEN1KMT2AALDH1A1TDP1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101180067-A Combination consisting of a histological or cytological fixing solution and of one or more photoactivatable compounds of the family of quinones, in particular, hypericin, hypocrellin a and hyprcrellin ERIC PELTIER (FR) 2008-05-14 CN disclosed