Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | EED | O75530 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2154795 | 0.89 | MAPT (0.49) | MAPTTP53HTR1ATSHRHTT | |
| SCHEMBL27693731 | 0.85 | KMT2A (0.43) | TSHRLMNA | |
| SCHEMBL2155613 | 0.84 | MAPT (0.49) | MAPTTP53HTR1ATSHRHTT | |
| SCHEMBL27713759 | 0.83 | TP53 (0.43) | MAPTTP53TSHRSMN1; SMN2DRD2 | |
| SCHEMBL27693727 | 0.83 | TP53 (0.42) | MAPTTP53HTR1ADRD2ALDH1A1 | |
| SCHEMBL2154790 | 0.81 | TP53 (0.45) | MAPTTP53HTR1ATSHRHTT | |
| SCHEMBL27693777 | 0.81 | POLB (0.39) | MAPTHTTHSD17B10POLB | |
| SCHEMBL27693900 | 0.81 | KDM4E (0.55) | MAPTTSHRHSD17B10ALDH1A1USP2 | |
| SCHEMBL16493628 | 0.80 | TP53 (0.56) | MAPTTP53HTR1ATSHRHTT | |
| SCHEMBL27693730 | 0.80 | LMNA (0.41) | MAPTHTTSMN1; SMN2HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101124213-A | Sulfonylamino cyclic derivatives and uses thereof | SERONO LAB (CH) | 2008-02-13 | — | — | CN | claimed |
| CN-101124213-A | Sulfonylamino cyclic derivatives and uses thereof | SERONO LAB (CH) | 2008-02-13 | — | — | CN | disclosed |