SCHEMBL27713617

SCHEMBL27713617

CCCCCOc1cc(N)ccc1C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.59
PTPN11 Q06124 6/20 0.52
S1PR3 Q99500 1/20 0.52
CYP1A2 P05177 1/20 0.52
CYP2D6 P10635 1/20 0.52
SCN1A P35498 1/20 0.52
SCN2A Q99250 1/20 0.52
SCN3A Q9NY46 1/20 0.52
PTPN1 P18031 1/20 0.49
PTPN6 P29350 1/20 0.49
PPARG P37231 1/20 0.49
PPARA Q07869 1/20 0.49
MEN1 O00255 1/20 0.49
NR1I2 O75469 1/20 0.49
LMNA P02545 1/20 0.49
CHRM2 P08172 1/20 0.49
CYP3A4 P08684 1/20 0.49
ADRA2A P08913 1/20 0.49
MAPT P10636 1/20 0.49
OPRK1 P41145 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27733996 0.98 ALDH1A1 (0.58) ALDH1A1PTPN11S1PR3CYP1A2CYP2D6
SCHEMBL4612211 0.97 ALDH1A1 (0.63) ALDH1A1PTPN11S1PR3CYP1A2CYP2D6
SCHEMBL730027 0.91 ALDH1A1 (0.63) ALDH1A1S1PR3CYP1A2CYP2D6SCN1A
SCHEMBL9363457 0.86 PTPN11 (0.57) ALDH1A1PTPN11S1PR3CYP1A2CYP2D6
SCHEMBL28193088 0.84 PTPN11 (0.66) ALDH1A1PTPN11TP53TSHRPLA2G4B
SCHEMBL578910 0.84 ALDH1A1 (0.67) ALDH1A1CYP1A2CYP2D6SCN1ASCN2A
SCHEMBL22117 0.84 ALDH1A1 (0.54) ALDH1A1CYP1A2CYP2D6SCN1ASCN2A
SCHEMBL17416884 0.84 ALDH1A1 (0.54) ALDH1A1CYP1A2CYP2D6SCN1ASCN2A
SCHEMBL7820620 0.83 PTPN11 (0.64) PTPN11S1PR3TP53TSHRPLA2G4B
SCHEMBL5492191 0.83 PTPN11 (0.64) PTPN11S1PR3TP53TSHRPLA2G4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101186577-A Liquid crystal monomer with reaction character and preparation method thereof NORTHWEST IND UNIVERSITY (CN) 2008-05-28 CN disclosed