Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | CTSS | P25774 | 5/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2155004 | 0.88 | CTSS (0.52) | KDM4EMAPTALDH1A1HSD17B10CTSS | |
| SCHEMBL4956424 | 0.86 | KDM4E (0.57) | KDM4EMAPTALDH1A1HSD17B10CTSS | |
| SCHEMBL27693735 | 0.85 | KDM4E (0.58) | KDM4EMAPTALDH1A1HSD17B10CTSS | |
| SCHEMBL27693728 | 0.84 | KDM4E (0.58) | KDM4EMAPTALDH1A1HSD17B10CTSS | |
| SCHEMBL2156099 | 0.82 | KDM4E (0.55) | KDM4EMAPTALDH1A1HSD17B10CTSS | |
| SCHEMBL27693900 | 0.82 | KDM4E (0.55) | KDM4EMAPTALDH1A1HSD17B10CTSS | |
| SCHEMBL2155000 | 0.79 | KDM4E (0.51) | KDM4EMAPTALDH1A1HSD17B10CTSS | |
| SCHEMBL27693768 | 0.78 | MAPT (0.47) | MAPTALDH1A1TP53TSHRMAPK1 | |
| SCHEMBL27693734 | 0.77 | KMT2A (0.44) | MAPTALDH1A1TP53PKMMEN1 | |
| SCHEMBL2156397 | 0.76 | KDM4E (0.57) | KDM4EMAPTALDH1A1HSD17B10CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101124213-A | Sulfonylamino cyclic derivatives and uses thereof | SERONO LAB (CH) | 2008-02-13 | — | — | CN | claimed |
| CN-101124213-A | Sulfonylamino cyclic derivatives and uses thereof | SERONO LAB (CH) | 2008-02-13 | — | — | CN | disclosed |