Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | CXCR3 | P49682 | 10/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | F13A1 | P00488 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | TGM1 | P22735 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27693726 | 0.97 | KDM4E (0.49) | CYP3A4MMP13CXCR3SMN1; SMN2HPGD | |
| SCHEMBL2155282 | 0.90 | CYP3A4 (0.48) | CYP3A4MMP13CXCR3SMN1; SMN2HPGD | |
| SCHEMBL2156913 | 0.87 | KDM4E (0.47) | CYP3A4MMP13CXCR3SMN1; SMN2HPGD | |
| SCHEMBL27693739 | 0.87 | TP53 (0.42) | CYP3A4MMP13KDM4E | |
| SCHEMBL2156843 | 0.85 | CYP3A4 (0.49) | CYP3A4MMP13CXCR3SMN1; SMN2HPGD | |
| SCHEMBL27693900 | 0.83 | KDM4E (0.55) | HPGDKDM4EF13A1TGM2TGM1 | |
| SCHEMBL2156421 | 0.83 | KDM4E (0.49) | CYP3A4MMP13CXCR3SMN1; SMN2HPGD | |
| SCHEMBL2155277 | 0.83 | CYP3A4 (0.58) | CYP3A4MMP13CXCR3SMN1; SMN2HPGD | |
| SCHEMBL5507351 | 0.82 | CXCR3 (0.53) | CYP3A4MMP13CXCR3SMN1; SMN2HPGD | |
| SCHEMBL2156908 | 0.80 | CYP3A4 (0.56) | CYP3A4MMP13CXCR3SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101124213-A | Sulfonylamino cyclic derivatives and uses thereof | SERONO LAB (CH) | 2008-02-13 | — | — | CN | claimed |
| CN-101124213-A | Sulfonylamino cyclic derivatives and uses thereof | SERONO LAB (CH) | 2008-02-13 | — | — | CN | disclosed |