Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27693768 | 0.92 | MAPT (0.47) | LMNAKMT2AMAPTALDH1A1GAA | |
| SCHEMBL27693734 | 0.90 | KMT2A (0.44) | KMT2AMAPTALDH1A1TP53MEN1 | |
| SCHEMBL2156466 | 0.89 | HDAC3 (0.45) | LMNAKMT2AMAPTALDH1A1GAA | |
| SCHEMBL4959154 | 0.86 | ALDH1A1 (0.44) | LMNAKMT2AMAPTALDH1A1GAA | |
| SCHEMBL2155679 | 0.84 | HDAC3 (0.45) | LMNAKMT2AMAPTALDH1A1GAA | |
| SCHEMBL2156463 | 0.81 | CYP3A4 (0.48) | LMNAKMT2AMAPTALDH1A1GAA | |
| SCHEMBL2155016 | 0.80 | MAPT (0.48) | LMNAKMT2AMAPTALDH1A1GAA | |
| SCHEMBL2154943 | 0.79 | GFER (0.45) | KMT2AMAPTALDH1A1TP53MEN1 | |
| SCHEMBL27713759 | 0.79 | TP53 (0.43) | LMNAKMT2AMAPTTP53MEN1 | |
| SCHEMBL27693727 | 0.78 | TP53 (0.42) | LMNAKMT2AMAPTALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101124213-A | Sulfonylamino cyclic derivatives and uses thereof | SERONO LAB (CH) | 2008-02-13 | — | — | CN | claimed |
| CN-101124213-A | Sulfonylamino cyclic derivatives and uses thereof | SERONO LAB (CH) | 2008-02-13 | — | — | CN | disclosed |