Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 3/20 | 0.42 |
| ▸ | MMP14 | P50281 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2155065 | 0.92 | TP53 (0.46) | TP53MMP13MMP14CYP3A4LMNA | |
| SCHEMBL2156215 | 0.90 | MMP13 (0.46) | TP53MMP13MMP14CYP3A4LMNA | |
| SCHEMBL27693798 | 0.88 | MMP13 (0.45) | TP53MMP13MMP14CYP3A4LMNA | |
| SCHEMBL28770879 | 0.88 | MMP13 (0.45) | TP53MMP13MMP14CYP3A4LMNA | |
| SCHEMBL27693778 | 0.88 | MMP13 (0.46) | TP53MMP13MMP14CYP3A4POLB | |
| SCHEMBL2155248 | 0.84 | TP53 (0.42) | TP53LMNAMAPT | |
| SCHEMBL2155126 | 0.82 | ATM (0.43) | LMNAMAPT | |
| SCHEMBL2155141 | 0.82 | TP53 (0.41) | TP53MMP13MMP14CYP3A4LMNA | |
| SCHEMBL2154777 | 0.81 | MMP13 (0.46) | TP53MMP13MMP14CYP3A4LMNA | |
| SCHEMBL2155021 | 0.80 | MMP13 (0.48) | TP53MMP13MMP14CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101124213-A | Sulfonylamino cyclic derivatives and uses thereof | SERONO LAB (CH) | 2008-02-13 | — | — | CN | disclosed |