SCHEMBL27713804

SCHEMBL27713804

O=C1C=CC(=O)C(C=NO)=C1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERBB2 P04626 1/20 0.37
TDP1 Q9NUW8 3/20 0.36
ALDH1A1 P00352 2/20 0.36
RECQL P46063 2/20 0.36
MEN1 O00255 1/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
ALOX12 P18054 1/20 0.36
KMT2A Q03164 1/20 0.36
SNCA P37840 1/20 0.31
MAOA P21397 2/20 0.30
MAOB P27338 2/20 0.30
BCHE P06276 1/20 0.30
POLB P06746 1/20 0.30
ACHE P22303 1/20 0.30
APEX1 P27695 1/20 0.30
MAPK1 P28482 1/20 0.30
CASP1 P29466 1/20 0.30
BLM P54132 1/20 0.30
MDM2 Q00987 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL48973 0.70 TDP1 (0.42) ERBB2TDP1ALDH1A1RECQLMEN1
SCHEMBL16947211 0.69 ALDH1A1 (0.40) ERBB2TDP1ALDH1A1RECQLMEN1
SCHEMBL5959263 0.69 MAPT (0.40) ERBB2TDP1ALDH1A1RECQLMEN1
SCHEMBL9115531 0.65 SNCA (0.44) TDP1ALDH1A1RECQLMEN1MAPT
SCHEMBL9115527 0.65 SNCA (0.44) TDP1ALDH1A1RECQLMEN1MAPT
SCHEMBL2365220 0.65 MAPT (0.37) ERBB2TDP1ALDH1A1RECQLMEN1
SCHEMBL8627021 0.65 ERBB2 (0.38) ERBB2TDP1ALDH1A1RECQLMEN1
SCHEMBL18235958 0.61 ERBB2 (0.34) ERBB2TDP1ALDH1A1RECQLMEN1
SCHEMBL221723 0.59
SCHEMBL28134388 0.59 MAPT (0.46) ERBB2TDP1ALDH1A1RECQLMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101088999-A Process of synthesizing 3-amino quinine dihydrochloride UNIV WUHAN TECH (CN) 2007-12-19 CN claimed
CN-116789971-A Preparation method and application of normal-temperature self-healing antifouling resin containing double antifouling factors 浙江省海洋开发研究院 2023-09-22 CN disclosed
CN-101970438-A Novel 1, 4-diaza-bicyclo [3.2.2] nonyl pyrimidine derivatives and their medical use NEUROSEARCH AS 2011-02-09 CN disclosed
CN-101855223-A Novel 1,4-diaza-bicyclo[3.2.2]nonyl pyrimidine derivatives and their medical use NEUROSEARCH AS 2010-10-06 CN disclosed
CN-101088999-A Process of synthesizing 3-amino quinine dihydrochloride UNIV WUHAN TECH (CN) 2007-12-19 CN disclosed