Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 20/20 | 1.00 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.64 |
| ▸ | KIT | P10721 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13956330 | 1.00 | FLT3 (1.00) | FLT3PDGFRBKIT | |
| SCHEMBL13955966 | 0.98 | FLT3 (1.00) | FLT3PDGFRBKIT | |
| SCHEMBL13955967 | 0.90 | FLT3 (1.00) | FLT3PDGFRBKIT | |
| SCHEMBL13956294 | 0.88 | FLT3 (0.85) | FLT3PDGFRBKIT | |
| SCHEMBL5921851 | 0.88 | FLT3 (0.78) | FLT3PDGFRBKIT | |
| SCHEMBL5921852 | 0.88 | FLT3 (0.78) | FLT3PDGFRBKIT | |
| SCHEMBL14597015 | 0.87 | FLT3 (0.78) | FLT3PDGFRBKIT | |
| SCHEMBL4960587 | 0.86 | FLT3 (0.78) | FLT3PDGFRBKIT | |
| SCHEMBL13956856 | 0.85 | FLT3 (0.81) | FLT3PDGFRBKIT | |
| SCHEMBL4959842 | 0.85 | FLT3 (0.73) | FLT3PDGFRBKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101242843-A | Aminopyrimidines as kinase modulators | JANSSEN PHARMACEUTICA NV (BE) | 2008-08-13 | — | — | CN | disclosed |
| CN-101242837-A | Synergistic modulation of FLT3 kinase with aminopyrimidine kinase modulators and farnesyl transferase inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2008-08-13 | — | — | CN | disclosed |