Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 20/20 | 0.81 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.49 |
| ▸ | KIT | P10721 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13956294 | 0.90 | FLT3 (0.85) | FLT3PDGFRBKIT | |
| SCHEMBL13955967 | 0.89 | FLT3 (1.00) | FLT3PDGFRBKIT | |
| SCHEMBL13955966 | 0.87 | FLT3 (1.00) | FLT3PDGFRBKIT | |
| SCHEMBL14597002 | 0.86 | FLT3 (0.78) | FLT3PDGFRBKIT | |
| SCHEMBL27713847 | 0.85 | FLT3 (1.00) | FLT3PDGFRBKIT | |
| SCHEMBL13956330 | 0.85 | FLT3 (1.00) | FLT3PDGFRBKIT | |
| SCHEMBL13955963 | 0.84 | FLT3 (1.00) | FLT3PDGFRBKIT | |
| SCHEMBL27736264 | 0.81 | FLT3 (1.00) | FLT3PDGFRBKIT | |
| SCHEMBL14597000 | 0.81 | FLT3 (1.00) | FLT3PDGFRBKIT | |
| SCHEMBL3888124 | 0.79 | FLT3 (0.71) | FLT3PDGFRBKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1898917-B1 | AMINOPYRIMIDINES AS KINASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2009-01-14 | — | — | EP | disclosed |
| US-20070021435-A1 | AMINOPYRIMIDINES AS KINASE MODULATORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-01-25 | — | — | US | disclosed |
| US-20070021435-A1 | AMINOPYRIMIDINES AS KINASE MODULATORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021435-A1 | AMINOPYRIMIDINES AS KINASE MODULATORS | FLT3, KIT, TK1 | FLT3 1/4885PDGFRB 22/4885KIT 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.