Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | HTR3B | O95264 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28175905 | 0.80 | TPMT (0.39) | TPMTALDH1A1HTTNPSR1RXRA | |
| SCHEMBL2072660 | 0.79 | TPMT (0.52) | TPMTALDH1A1HTTNPSR1RXRA | |
| SCHEMBL5846489 | 0.75 | TPMT (0.39) | TPMTALDH1A1HTTNPSR1RXRA | |
| SCHEMBL1331263 | 0.74 | — | — | |
| SCHEMBL186056 | 0.74 | — | — | |
| SCHEMBL1332066 | 0.74 | — | — | |
| SCHEMBL347092 | 0.72 | TPMT (0.59) | TPMTALDH1A1NPSR1RXRARXRB | |
| SCHEMBL2437624 | 0.72 | TPMT (0.46) | TPMTALDH1A1HTTNPSR1RXRA | |
| SCHEMBL28121434 | 0.72 | TPMT (0.46) | TPMTALDH1A1HTTNPSR1RXRA | |
| SCHEMBL27720237 | 0.72 | TPMT (0.46) | TPMTALDH1A1HTTNPSR1RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101250173-B | Preparation method of spiromesifen | UNIV ZHEJIANG | 2010-06-16 | — | — | CN | disclosed |
| CN-101250173-A | Preparation method of spiromesifen | UNIV ZHEJIANG (CN) | 2008-08-27 | — | — | CN | disclosed |