Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 1/20 | 0.30 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28752828 | 0.72 | — | — | |
| SCHEMBL27589375 | 0.72 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL2033825 | 0.69 | — | — | |
| SCHEMBL1356364 | 0.69 | — | — | |
| SCHEMBL467548 | 0.67 | — | — | |
| SCHEMBL28812635 | 0.67 | — | — | |
| SCHEMBL31158383 | 0.67 | — | — | |
| SCHEMBL3082231 | 0.66 | — | — | |
| SCHEMBL29090819 | 0.65 | PSMD14 (0.30) | PSMD14COPS5 | |
| SCHEMBL29090817 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102746301-A | 8-phenyl-7,8-dihydropyrido[2,3-d]pyrimidin-7-ones and their use as pharmaceuticals | GLAXO GROUP LTD | 2012-10-24 | — | — | CN | disclosed |
| CN-102746299-A | 8-PHENYL-7,8-DIHYDROPYRIDO[2,3-d]PYRIMIDIN-7-ONES AND THEIR USE AS PHARMACEUTICALS | GLAXO GROUP LTD | 2012-10-24 | — | — | CN | disclosed |
| CN-102746300-A | 8-phenyl-7,8-dihydropyridines[2,3-d]pyrimidine-7-ketone and uses as medicament | GLAXO GROUP LTD | 2012-10-24 | — | — | CN | disclosed |
| CN-101258148-A | 8-phenyl-7, 8-dihydropyrido [2, 3-d ] pyrimidin-7-ones and their use as medicaments | GLAXO GROUP LTD (GB) | 2008-09-03 | — | — | CN | disclosed |