Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 10/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.52 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.52 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2788977 | 0.90 | PDE4A (0.64) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2770833 | 0.88 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2785376 | 0.88 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2786982 | 0.87 | PDE4D (0.41) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2771247 | 0.86 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4DCYP1A1 | |
| SCHEMBL2789925 | 0.86 | PDE4A (0.52) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2773724 | 0.85 | CYP1A1 (0.46) | PDE4APDE4BPDE4CPDE4DCYP1A1 | |
| SCHEMBL2772270 | 0.84 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2785396 | 0.83 | KDM4E (0.42) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2771449 | 0.82 | PDE4A (0.76) | PDE4APDE4BPDE4CPDE4DPDE7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010076564-A2 | ISOCHROMENONES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2010-07-08 | — | — | WO | disclosed |