Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | CDC25A | P30304 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | CDC25C | P30307 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2770600 | 0.91 | PDE4A (0.47) | TDP1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2771444 | 0.89 | SMPD1 (0.42) | KDM4EMAOBPDE4APDE4BPDE4C | |
| SCHEMBL2773803 | 0.89 | PDE4A (0.41) | KDM4EMAOBPDE4APDE4BPDE4C | |
| SCHEMBL2773724 | 0.89 | CYP1A1 (0.46) | KDM4ECYP1A1CYP1A2PDE4APDE4B | |
| SCHEMBL2771247 | 0.89 | PDE4A (0.46) | KDM4ECYP1A1CYP1A2PDE4APDE4B | |
| SCHEMBL2787889 | 0.86 | PDE4A (0.38) | KDM4EMAOBPDE4APDE4BPDE4C | |
| SCHEMBL2787046 | 0.86 | PTGES (0.40) | TDP1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2786982 | 0.86 | PDE4D (0.41) | KDM4ETDP1C5AR1CYP1A1CYP1A2 | |
| SCHEMBL2774638 | 0.85 | TP53 (0.40) | KDM4ETDP1CYP1A1CYP1A2PDE4A | |
| SCHEMBL2788405 | 0.84 | PDE4A (0.51) | KDM4EPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010076564-A2 | ISOCHROMENONES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2010-07-08 | — | — | WO | disclosed |