Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL222107 | 0.91 | ACHE (0.76) | ACHEBCHE | |
| SCHEMBL27981863 | 0.87 | ACHE (0.83) | ACHEBCHE | |
| SCHEMBL9411370 | 0.85 | ACHE (0.64) | ACHEBCHE | |
| SCHEMBL28813999 | 0.85 | ACHE (0.83) | ACHEBCHE | |
| SCHEMBL9411440 | 0.81 | ACHE (0.78) | ACHEBCHE | |
| SCHEMBL27981988 | 0.81 | ACHE (0.84) | ACHEBCHE | |
| Maleic Acid SCHEMBL27339121 | 0.81 | ACHE (0.72) | ACHEBCHE | |
| Maleic Acid SCHEMBL27339122 | 0.81 | ACHE (0.72) | ACHEBCHE | |
| SCHEMBL9411418 | 0.79 | ACHE (0.63) | ACHE | |
| SCHEMBL27981554 | 0.79 | ACHE (0.83) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101316853-B | Benzothiazole and thiazolopyridine as SIRTUIN modulators | SIRTRIS PHARMACEUTICALS INC | 2014-09-24 | — | — | CN | disclosed |
| CN-103145738-A | Imidazo [2,1-b] thiayole derivatives as SIRTUIN modulating compounds | SIRTRIS PHARMACEUTICALS INC | 2013-06-12 | — | — | CN | disclosed |
| CN-101316853-A | Benzothiazole and thiazolopyridine as SIRTUIN modulators | SIRTRIS PHARMACEUTICALS INC (US) | 2008-12-03 | — | — | CN | disclosed |
| CN-101282974-A | Benzimidazole derivatives as SIRTUIN modulators | SIRTRIS PHARMACEUTICALS INC (US) | 2008-10-08 | — | — | CN | disclosed |
| CN-101277963-A | Benzimidazole derivatives as SIRTUIN modulators | SIRTIS PHARMACEUTICALS INC (US) | 2008-10-01 | — | — | CN | disclosed |
| CN-101277965-A | Imidazo [2, 1-b ] thiazole derivatives as SIRTUIN modulating compounds | SIRTRIS PHARMACEUTICALS INC (US) | 2008-10-01 | — | — | CN | disclosed |