Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3140803 | 0.93 | TP53 (0.44) | TP53ALDH1A1TSHRL3MBTL1THRB | |
| Trifluoroacetic Acid SCHEMBL7793452 | 0.90 | TP53 (0.42) | TP53ALDH1A1TSHRL3MBTL1THRB | |
| Trifluoroacetic Acid SCHEMBL1035693 | 0.90 | TP53 (0.42) | TP53ALDH1A1TSHRL3MBTL1THRB | |
| Trifluoroacetic Acid SCHEMBL28063473 | 0.88 | TP53 (0.65) | TP53ALDH1A1TSHRL3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL29019093 | 0.88 | TP53 (0.40) | TP53ALDH1A1TSHRL3MBTL1THRB | |
| Trifluoroacetic Acid SCHEMBL1833665 | 0.88 | TP53 (0.40) | TP53ALDH1A1TSHRDPP4DPP8 | |
| Trifluoroacetic Acid SCHEMBL30704791 | 0.85 | TP53 (0.38) | TP53ALDH1A1TSHRL3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL29019090 | 0.85 | TP53 (0.38) | TP53ALDH1A1TSHRL3MBTL1CA2 | |
| Trifluoroacetic Acid SCHEMBL3055318 | 0.84 | ALDH1A1 (0.38) | TP53ALDH1A1TSHRL3MBTL1THRB | |
| Trifluoroacetic Acid SCHEMBL3416090 | 0.84 | SLC7A5 (0.41) | TP53ALDH1A1TSHRL3MBTL1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101094847-B | Aryloxy-substituted benzimidazole derivatives | BANYU PHARMA CO LTD | 2011-06-15 | — | — | CN | disclosed |
| CN-101094847-A | Aryloxy-substituted benzimidazole derivatives | BANYU PHARMA CO LTD (JP) | 2007-12-26 | — | — | CN | disclosed |