Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27908096 | 0.83 | MEN1 (0.33) | MEN1ALDH1A1KMT2ATSHR | |
| SCHEMBL28704256 | 0.81 | BRD4 (0.32) | — | |
| SCHEMBL28036513 | 0.79 | MEN1 (0.34) | MEN1ALDH1A1KMT2ATSHRMAPT | |
| SCHEMBL28969686 | 0.78 | — | — | |
| SCHEMBL28775423 | 0.78 | MEN1 (0.30) | MEN1ALDH1A1KMT2A | |
| SCHEMBL27698482 | 0.78 | CDK2 (0.30) | — | |
| SCHEMBL27843227 | 0.77 | — | — | |
| SCHEMBL27679469 | 0.77 | LMNA (0.36) | — | |
| SCHEMBL27800053 | 0.76 | RPS6KA5 (0.30) | — | |
| SCHEMBL27703704 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101215289-A | 3-substituted phenyl-pyrazolo[3,4-d][1,2,3]triazin-4-one compounds with PPO restraining activity and weeding activity | UNIV NANKAI (CN) | 2008-07-09 | — | — | CN | claimed |
| CN-104529900-A | Bactericidal activity of 1-substituted-N-substituted phenyl-5-amidogen-1H-pyrazole-4-formamide compound | UNIV NANKAI | 2015-04-22 | — | — | CN | disclosed |
| CN-102216285-B | Tetrasubstituted pyridazine hedgehog pathway antagonists | LILLY CO ELI | 2014-08-13 | — | — | CN | disclosed |
| CN-102216285-A | Tetrasubstituted pyridazine hedgehog pathway antagonists | LILLY CO ELI | 2011-10-12 | — | — | CN | disclosed |
| CN-101215289-A | 3-substituted phenyl-pyrazolo[3,4-d][1,2,3]triazin-4-one compounds with PPO restraining activity and weeding activity | UNIV NANKAI (CN) | 2008-07-09 | — | — | CN | disclosed |