Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 2/20 | 0.57 |
| ▸ | FNTB | P49356 | 2/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.57 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.46 |
| ▸ | PPARG | P37231 | 7/20 | 0.46 |
| ▸ | PPARD | Q03181 | 7/20 | 0.46 |
| ▸ | PPARA | Q07869 | 7/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TLR2 | O60603 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | FABP4 | P15090 | 2/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6545373 | 0.98 | FNTA (0.60) | FNTAFNTBTHRBPGGT1BAKR1B1 | |
| SCHEMBL2064793 | 0.94 | FNTA (0.48) | FNTAFNTBTHRBPGGT1BAKR1B1 | |
| SCHEMBL4152299 | 0.85 | FFAR3 (0.42) | FNTAFNTBTHRBPGGT1BAKR1B1 | |
| SCHEMBL4152302 | 0.85 | FFAR3 (0.42) | FNTAFNTBTHRBPGGT1BAKR1B1 | |
| SCHEMBL4152296 | 0.85 | FFAR3 (0.42) | FNTAFNTBTHRBPGGT1BAKR1B1 | |
| SCHEMBL183671 | 0.82 | FNTA (0.71) | FNTAFNTBTHRBPGGT1BAKR1B1 | |
| SCHEMBL555048 | 0.82 | FNTA (0.71) | FNTAFNTBTHRBPGGT1BAKR1B1 | |
| SCHEMBL555050 | 0.82 | FNTA (0.71) | FNTAFNTBTHRBPGGT1BAKR1B1 | |
| SCHEMBL13144808 | 0.81 | FNTA (0.59) | FNTAFNTBTHRBPGGT1BAKR1B1 | |
| SCHEMBL30007255 | 0.81 | FNTA (0.64) | FNTAFNTBTHRBPGGT1BGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8067586-B2 | Fused heteroaryl derivatives | ASTELLAS PHARMA INC. (JP) | 2011-11-29 | — | — | US | disclosed |
| US-20100137584-A1 | FUSED HETEROARYL DERIVATIVES | HAYAKAWA MASAHIKO | 2010-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137584-A1 | FUSED HETEROARYL DERIVATIVES | PIK3CD, PIK3R3, PIK3C2A | FNTA 1183/4885FNTB 1861/4885THRB 2794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.