Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 4/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | FNTA | P49354 | 2/20 | 0.38 |
| ▸ | FNTB | P49356 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.36 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4152296 | 1.00 | FFAR3 (0.42) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL4152302 | 1.00 | FFAR3 (0.42) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL2064793 | 0.86 | FNTA (0.48) | ALDH1A1FNTAFNTBCES2CES1 | |
| SCHEMBL277151 | 0.85 | FNTA (0.57) | ALDH1A1FNTAFNTBCES2CES1 | |
| SCHEMBL3357465 | 0.83 | ALDH1A1 (0.40) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL6545373 | 0.83 | FNTA (0.60) | ALDH1A1FNTAFNTBCES2CES1 | |
| SCHEMBL2636263 | 0.82 | GRIK1 (0.40) | FFAR3ALDH1A1FNTAFNTBTHRB | |
| SCHEMBL5596730 | 0.82 | GRIK1 (0.40) | FFAR3ALDH1A1FNTAFNTBTHRB | |
| SCHEMBL4621796 | 0.81 | FFAR3 (0.42) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL8884306 | 0.81 | FFAR3 (0.42) | FFAR3HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507561-B1 | Thermoplastic resin compositions | NOF CORP (JP) | 1996-06-26 | — | — | EP | claimed |
| EP-0370753-B1 | Modified polyolefin particles and process for preparation thereof | MITSUI PETROCHEMICAL IND (JP) | 1995-01-18 | — | — | EP | claimed |
| US-20090137557-A1 | Calcilytic Compounds | SMITHKLINE BEECHAM CORPORATION | 2009-05-28 | — | — | US | disclosed |
| EP-1951244-A2 | CALCILYTIC COMPOUNDS | SmithKline Beecham Corporation (US) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007062370-A2 | CALCILYTIC COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137557-A1 | Calcilytic Compounds | CALCR, SOST, CALCB | FFAR3 3796/4885HDAC3 4088/4885HDAC1 4096/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.