Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 13/20 | 0.44 |
| ▸ | F9 | P00740 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 6/20 | 0.42 |
| ▸ | PRP4K | Q13523 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27715497 | 0.90 | SLC9A1 (0.56) | SLC9A1F9DYRK1ADYRK1B | |
| SCHEMBL27715569 | 0.90 | SLC9A1 (0.56) | SLC9A1F9DYRK1ADYRK1B | |
| SCHEMBL3813474 | 0.90 | F9 (0.57) | SLC9A1F9DYRK1ADYRK1B | |
| SCHEMBL27695588 | 0.89 | SLC9A1 (0.42) | SLC9A1F9DYRK1ADYRK1BPRP4K | |
| SCHEMBL27695553 | 0.88 | SLC9A1 (0.47) | SLC9A1F9 | |
| SCHEMBL3820981 | 0.86 | SLC9A1 (0.48) | SLC9A1DYRK1A | |
| SCHEMBL3814870 | 0.85 | SLC9A1 (0.47) | SLC9A1F9 | |
| SCHEMBL28767338 | 0.85 | SLC9A1 (0.56) | SLC9A1F9DYRK1A | |
| SCHEMBL27715654 | 0.85 | F9 (0.46) | SLC9A1F9DYRK1ADYRK1B | |
| SCHEMBL27715549 | 0.85 | SLC9A1 (0.47) | SLC9A1F9DYRK1ADYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101137641-B | Benzothiophen-2-carbonylguanidine derivatives, preparation thereof, and pharmaceutical composition containing the same | KOREA RES INST CHEM TECH | 2010-11-24 | — | — | CN | disclosed |
| CN-101137641-A | Benzothiophen-2-carbonylguanidine derivatives, preparation thereof, and pharmaceutical composition containing the same | KOREA RES INST CHEM TECH (KR) | 2008-03-05 | — | — | CN | disclosed |