Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27715987 | 0.86 | HSP90AB1 (0.41) | HSP90AB1 | |
| SCHEMBL27715989 | 0.84 | HSP90AB1 (0.47) | HSP90AB1 | |
| SCHEMBL2309822 | 0.83 | HSP90AB1 (0.41) | HSP90AB1 | |
| SCHEMBL2309814 | 0.83 | HSP90AB1 (0.41) | HSP90AB1 | |
| SCHEMBL2313612 | 0.82 | HSP90AB1 (0.46) | HSP90AB1 | |
| SCHEMBL27715988 | 0.78 | HSP90AB1 (0.60) | HSP90AB1 | |
| SCHEMBL2313325 | 0.76 | KEAP1 (0.39) | — | |
| SCHEMBL27776596 | 0.73 | PDK2 (0.40) | — | |
| SCHEMBL2311299 | 0.73 | MEN1 (0.40) | HSP90AB1 | |
| SCHEMBL2311295 | 0.73 | MEN1 (0.40) | HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101203518-B | Fluorene derivative, composition containing the same and use thereof | AVENTIS PHARMA SA | 2013-07-24 | — | — | CN | disclosed |
| CN-101203518-A | Novel fluorene derivatives, compositions containing same and uses thereof | AVENTIS PHARMA SA (FR) | 2008-06-18 | — | — | CN | disclosed |