Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | FPR3 | P25089 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27737205 | 0.91 | PPARG (0.43) | PPARGCNR1CNR2PDE4APDE4B | |
| SCHEMBL27716279 | 0.90 | PPARG (0.44) | PPARGCNR1CNR2PDE4APDE4B | |
| SCHEMBL27716319 | 0.89 | PPARG (0.41) | PPARG | |
| SCHEMBL27716255 | 0.88 | PPARG (0.44) | PPARGCNR1CNR2PDE4APDE4B | |
| SCHEMBL28771281 | 0.87 | PPARG (0.43) | PPARGCNR1CNR2MTNR1A | |
| SCHEMBL28771266 | 0.87 | PPARG (0.43) | PPARGCNR1CNR2MTNR1A | |
| SCHEMBL27737138 | 0.85 | PPARG (0.44) | PPARGCNR1CNR2 | |
| SCHEMBL27737207 | 0.81 | PPARG (0.44) | PPARGCNR1CNR2PDE4APDE4B | |
| SCHEMBL27716275 | 0.81 | PPARG (0.40) | PPARG | |
| SCHEMBL27716322 | 0.80 | PPARG (0.41) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101282725-A | Therapeutic agent for diabetes | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2008-10-08 | — | — | CN | disclosed |